- Balanced and sustainable development of the whole territory of the Republic of Macedonia based on the model of polycentric development;
- Lowered disparities between and within the planning regions and improved quality of life of all citizens;
- Increased competitiveness of the planning regions through the strengthening of their innovation capacity, optimal utilization and valuing of natural resources, human resources and economic specifics of the different regions;
- Preservation and development of the specific identity of the individual planning regions, as well as their affirmation and development;
- Revitalization of villages and development of the areas with specific development needs;
- Support of inter-municipal and cross-border cooperation for promotion of equitable regional development.